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Introduction and Principle
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Introduction
Percutaneous Cementoplasty (PC, vertebral packing, vertebroplasty) with acrylic glue (polymethylmethacrylate: PMMA) is a procedure aimed at preventing vertebral body crushing and pain in patients with pathological vertebral bodies. Percutaneous cementoplasty seems to be promising in pain therapy for patients with bone failure.
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Principle
The pain reducing effect of cement cannot be explained by the consolidation of the pathological bone alone. In fact, good pain relief is obtained after injection of only 2 ml of polymethylmethacrylate in metastasis. In these cases the consolidation effect is minimal. The polymethylmethacrylate is cytotoxic due to its chemical and thermal effect during polymerization. The temperature during polymerization is high enough to produce coagulation of the tumoral cells. Therefore, good pain relief can be obtained with a low volume of glue.
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